CAMK2N1

Across TCGA patient cohorts, CAMK2N1 mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAMK2N1-associated genes across cancer lineages are RNU2-61P, RNVU1-28, and RNY4P19. Each is linked with CAMK2N1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMK2N1-to-partner and partner-to-CAMK2N1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-61P grouped by CAMK2N1-low versus CAMK2N1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK2N1→partner) and Y-score (partner→CAMK2N1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU2-61P →	+0.371	+3.399	.004	.005	3	2
UCEC	RNVU1-28 →	+1.378	+2.857	<.001	.002	3	1
UCEC	RNY4P19 →	+0.754	+2.872	<.001	.002	3	1
UCEC	RNA5SP502 →	+0.971	+2.993	<.001	.002	3	1
UCEC	RNA5SP391 →	+0.359	+5.478	<.001	<.001	3	1
UCEC	RNU6-151P →	+0.545	+2.741	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

RNU2-61P by CAMK2N1 expression — UCEC

Explore this box plot interactively →