CAMK2N1

Across TCGA cell cohorts, CAMK2N1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,150 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CAMK2N1-associated GO terms across cancer lineages are Positive regulation of proteolysis, Protein localization to plasma membrane, and Hormone-mediated signaling pathway. Each is linked with CAMK2N1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CAMK2N1-to-partner and partner-to-CAMK2N1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteolysis grouped by CAMK2N1-low versus CAMK2N1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK2N1→partner) and Y-score (partner→CAMK2N1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of proteolysis →	+0.110	+2.096	<.001	<.001	3	13
BONE	Protein localization to plasma membrane →	+0.075	+1.963	.002	.006	3	11
PANCREAS	Hormone-mediated signaling pathway →	+0.056	+1.871	<.001	<.001	3	11
SOFT_TISSUE	Negative regulation of cell adhesion →	+0.074	+2.254	<.001	<.001	3	11
SKIN	Nuclear receptor-mediated signaling pathway →	+0.064	+2.031	<.001	<.001	3	11
URINARY_TRACT	IMP biosynthetic process →	-0.174	-2.191	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,150 associations by consensus.

Positive regulation of proteolysis by CAMK2N1 expression — PANCREAS

Explore this box plot interactively →