CAMK2N1

Across TCGA cell cohorts, CAMK2N1 mutation is significantly associated with the mutation status of many other genes, with 372 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CAMK2N1-associated genes across cancer lineages are C1orf52, ARL5A, and SGCB. Each is linked with CAMK2N1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAMK2N1-to-partner and partner-to-CAMK2N1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf52 grouped by CAMK2N1-low versus CAMK2N1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAMK2N1→partner) and Y-score (partner→CAMK2N1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C1orf52 →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	ARL5A →	+5.523	+5.523	.003	.003	1	1
LARGE_INTESTINE	SGCB →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	HPGDS →	+4.523	+5.087	.006	.006	1	1
LARGE_INTESTINE	HDAC11 →	+5.523	+5.523	.003	.003	1	1
LARGE_INTESTINE	RYBP →	+4.523	+5.087	.006	.006	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 372 associations by consensus.

C1orf52 by CAMK2N1 expression — LARGE_INTESTINE

Explore this box plot interactively →