CALR3

Across TCGA patient cohorts, CALR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,887 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CALR3-associated GO terms across cancer lineages are tRNA metabolic process, RNA modification, and mRNA 3'-end processing. Each is linked with CALR3 in more than 18 cancer types. Because this analysis shows association rather than direction, both CALR3-to-partner and partner-to-CALR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA metabolic process grouped by CALR3-low versus CALR3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALR3→partner) and Y-score (partner→CALR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA metabolic process →	+0.067	+0.211	<.001	<.001	3	19
STAD	RNA modification →	+0.066	+0.194	<.001	<.001	3	19
STAD	mRNA 3'-end processing →	+0.072	+0.186	<.001	<.001	3	19
STAD	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.060	+0.189	<.001	<.001	3	17
ESCA	Mitotic nuclear division →	+0.091	+0.170	<.001	<.001	3	16
STAD	Meiotic cell cycle process →	+0.035	+0.166	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,887 associations by consensus.

tRNA metabolic process by CALR3 expression — STAD

Explore this box plot interactively →