CALR3

Across TCGA cell cohorts, CALR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,920 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CALR3-associated GO terms across cancer lineages are Angiogenesis, Epithelial cell development, and Regulation of monoatomic cation transmembrane transport. Each is linked with CALR3 in more than 6 cancer types. Because this analysis shows association rather than direction, both CALR3-to-partner and partner-to-CALR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Angiogenesis grouped by CALR3-low versus CALR3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CALR3→partner) and Y-score (partner→CALR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Angiogenesis →	-0.092	-0.093	<.001	<.001	3	7
BONE	Epithelial cell development →	-0.145	-0.123	<.001	<.001	3	6
BONE	Regulation of monoatomic cation transmembrane transport →	-0.093	-0.122	<.001	<.001	3	6
BONE	Endodermal cell differentiation →	-0.141	-0.101	.004	.004	3	6
BONE	Regulation of potassium ion transport →	-0.107	-0.099	.002	.001	3	6
BONE	Positive regulation of epidermal cell differentiation →	+0.202	+0.091	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,920 associations by consensus.

Angiogenesis by CALR3 expression — BONE

Explore this box plot interactively →