CALML6

Across TCGA patient cohorts, CALML6 mutation is significantly associated with the RNA expression of many other genes, with 76 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CALML6-associated genes across cancer lineages are CICP28, MIR6783, and MRGPRX13P. Each is linked with CALML6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALML6-to-partner and partner-to-CALML6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CICP28 grouped by CALML6-low versus CALML6-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALML6→partner) and Y-score (partner→CALML6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	CICP28 →	+0.018	+5.108	<.001	.008	3	1
UCEC	MIR6783 →	+0.702	+3.102	<.001	.001	3	1
LIHC	MRGPRX13P →	+0.341	+5.878	<.001	.002	3	1
LIHC	MIR4655 →	+0.515	+6.008	<.001	.002	3	1
UCEC	OR5T3 →	+0.064	+3.329	.006	.005	3	1
UCEC	RNA5SP26 →	+0.218	+4.245	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

CICP28 by CALML6 expression — LIHC

Explore this box plot interactively →