CALHM6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CALHM6 mutation is significantly associated with the RNA expression of many other genes, with 2,258 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CALHM6-associated genes across cancer lineages are SH3PXD2A, ABHD5, and KLHL18. Each is linked with CALHM6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CALHM6-to-partner and partner-to-CALHM6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CALHM6→partner) and Y-score (partner→CALHM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSH3PXD2A →+0.643+3.467.001.00232
UCECABHD5 →+0.736+2.828<.001.00132
UCECKLHL18 →+0.714+3.742<.001<.00132
UCECMFN2 →+0.652+2.839<.001.00132
UCECPINK1-AS →+0.612+2.818<.001.00132
UCECSERAC1 →+0.649+2.818<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,258 associations by consensus.

Exploration