CACNG3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CACNG3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CACNG3-associated genes across cancer lineages are AVP, CABP5, and DEFB129. Each is linked with CACNG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNG3-to-partner and partner-to-CACNG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by CACNG3-low versus CACNG3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG3→partner) and Y-score (partner→CACNG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaAVP →+0.031+5.209<.001.00531
BLOOD_LymphomaCABP5 →+0.012+4.867<.001.00931
BLOOD_LymphomaDEFB129 →+0.043+6.247<.001<.00131
BLOOD_LymphomaMROH2B →+0.085+5.643<.001.00231
BLOOD_LymphomaKRTAP4-11 →+0.035+5.209<.001.00531
LARGE_INTESTINEOR10W1 →+0.022+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

AVP by CACNG3 expression — BLOOD_Lymphoma

Box plot of AVP in CACNG3-low vs CACNG3-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration