CACNG2

Across TCGA cell cohorts, CACNG2 mutation is significantly associated with the RNA expression of many other genes, with 143 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CACNG2-associated genes across cancer lineages are ITPK1, RNF125, and RHBDL1. Each is linked with CACNG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNG2-to-partner and partner-to-CACNG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITPK1 grouped by CACNG2-low versus CACNG2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG2→partner) and Y-score (partner→CACNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITPK1 →	+0.727	+3.169	<.001	.009	3	1
LARGE_INTESTINE	RNF125 →	+1.145	+3.234	<.001	.004	3	1
LARGE_INTESTINE	RHBDL1 →	+1.050	+3.364	<.001	.002	3	1
LARGE_INTESTINE	CRACD →	+1.121	+3.364	.001	.002	3	1
LARGE_INTESTINE	HINT3 →	+0.609	+3.169	.009	.009	3	1
LARGE_INTESTINE	SLC1A4 →	+1.100	+3.364	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 143 associations by consensus.

ITPK1 by CACNG2 expression — LARGE_INTESTINE

Explore this box plot interactively →