CACNG2

Across TCGA pan-cancer cohorts, CACNG2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CACNG2’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CACNG2 RNA is repressed in tumor relative to normal tissue. In most cancer types CACNG2 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, LUAD, and LUSC are the cancer types where CACNG2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CACNG2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.014	<.001	4	view →
LUAD	Male	II,III,IV	+0.186	.034	2	view →
LUSC	All	All	+0.033	.015	2	view →
BRCA	All	II,III,IV	−0.029	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

CACNG2–THCA

Open the THCA breakdown →