CACNB3

Across TCGA patient cohorts, CACNB3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,034 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CACNB3-associated genes across cancer lineages are OLFM2, SPEG, and ASPA. Each is linked with CACNB3 in more than 3 cancer types. Because this analysis shows association rather than direction, both CACNB3-to-partner and partner-to-CACNB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNB3 versus OLFM2 in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB3→partner) and Y-score (partner→CACNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	OLFM2 →	+2.640	+0.928	<.001	<.001	3	4
OV	SPEG →	+1.308	+0.835	<.001	.003	3	4
OV	ASPA →	+0.954	+1.084	.002	<.001	3	3
GBM	CNNM1 →	+0.734	+0.421	<.001	<.001	3	3
GBM	SNAP25 →	+1.789	+0.466	<.001	<.001	3	3
UCEC	DGKB →	+0.906	+0.523	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,034 associations by consensus.

CACNB3 vs OLFM2 — OV

Explore this scatter interactively →