CACNB3

Across TCGA cell cohorts, CACNB3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CACNB3-associated genes across cancer lineages are REG3G, KRTAP21-2, and USP17L20. Each is linked with CACNB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNB3-to-partner and partner-to-CACNB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG3G grouped by CACNB3-low versus CACNB3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB3→partner) and Y-score (partner→CACNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	REG3G →	+0.026	+4.867	.004	.009	3	1
BLOOD_Leukemia	KRTAP21-2 →	+0.115	+4.539	<.001	.007	3	1
BLOOD_Leukemia	USP17L20 →	+0.004	+4.539	<.001	.007	3	1
BLOOD_Leukemia	USP17L18 →	+0.004	+4.539	<.001	.007	3	1
BLOOD_Leukemia	WDR87 →	+0.060	+4.865	<.001	.001	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

REG3G by CACNB3 expression — BLOOD_Lymphoma

Explore this box plot interactively →