CACNA1S

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CACNA1S protein abundance is significantly associated with the RNA expression of many other genes, with 1,302 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CACNA1S-associated genes across cancer lineages are CTSG, GALNT16, and SLC8A3. Each is linked with CACNA1S in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNA1S-to-partner and partner-to-CACNA1S results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNA1S versus CTSG in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1S→partner) and Y-score (partner→CACNA1S) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCTSG →+1.319+0.946.003.00531
HNSCGALNT16 →+0.459+0.837.002<.00131
HNSCSLC8A3 →+0.518+0.881<.001<.00131
HNSCTCL1A →+0.763+0.675<.001.00131
HNSCBMP7 →-1.192-0.897.003.00131
HNSCEEF1A2 →+1.301+0.700<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,302 associations by consensus.

CACNA1S vs CTSG — HNSC

Per-sample scatter of CACNA1S vs CTSG in HNSC (Pearson r = 0.39).

Explore this scatter interactively →

Exploration