CACNA1S

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CACNA1S RNA expression is significantly associated with the go_rna of many other GO terms, with 523 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CACNA1S-associated GO terms across cancer lineages are RNA surveillance, RNA methylation, and Negative regulation of mRNA metabolic process. Each is linked with CACNA1S in more than 4 cancer types. Because this analysis shows association rather than direction, both CACNA1S-to-partner and partner-to-CACNA1S results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA surveillance grouped by CACNA1S-low versus CACNA1S-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1S→partner) and Y-score (partner→CACNA1S) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUERNA surveillance →+0.036+0.427.009.00835
SOFT_TISSUERNA methylation →+0.047+0.457<.001.00434
SOFT_TISSUENegative regulation of mRNA metabolic process →+0.084+0.830<.001.00534
SOFT_TISSUEGlobus pallidus development →+0.571+0.800.005.00834
SOFT_TISSUErRNA 3'-end processing →+0.055+0.424<.001.00934
LARGE_INTESTINEPositive regulation of myoblast differentiation →+0.092+0.029<.001.00725
Each partner links to its Q-omics profile. Showing the 6 strongest of 523 associations by consensus.

RNA surveillance by CACNA1S expression — SOFT_TISSUE

Box plot of RNA surveillance in CACNA1S-low vs CACNA1S-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration