CACNA1C-IT1

Across TCGA patient cohorts, CACNA1C-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,065 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CACNA1C-IT1-associated proteins across cancer lineages are MKI67_S357, TYMP_S50, and UBXN6. Each is linked with CACNA1C-IT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CACNA1C-IT1-to-partner and partner-to-CACNA1C-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNA1C-IT1 versus MKI67_S357 in LUAD, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1C-IT1→partner) and Y-score (partner→CACNA1C-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MKI67_S357 →	-1.058	-0.156	.001	.002	3	3
GBM	TYMP_S50 →	-1.019	-0.680	<.001	<.001	3	3
GBM	UBXN6 →	+0.271	+0.390	<.001	.003	3	3
GBM	SEPTIN11 →	+0.264	+0.569	<.001	<.001	3	3
PDAC	CENPF_S3054 →	-0.711	-0.133	.003	.004	3	3
UCEC	UTRN_S1866 →	+0.821	+0.539	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,065 associations by consensus.

CACNA1C-IT1 vs MKI67_S357 — LUAD

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