CACNA1C-AS4

Across TCGA pan-cancer cohorts, CACNA1C-AS4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CACNA1C-AS4’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where CACNA1C-AS4 RNA is repressed in tumor relative to normal tissue. In most cancer types CACNA1C-AS4 is over-expressed in tumor, although a few such as UCEC and LUSC show the opposite, repressed pattern.

UCEC and LUSC are the cancer types where CACNA1C-AS4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CACNA1C-AS4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.083	.012	4	view →
LUSC	Male	All	−0.042	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

CACNA1C-AS4–UCEC

Open the UCEC breakdown →