CABS1

Across TCGA cell cohorts, CABS1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CABS1-associated genes across cancer lineages are PSKH2, TRIM49C, and KRT28. Each is linked with CABS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CABS1-to-partner and partner-to-CABS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSKH2 grouped by CABS1-low versus CABS1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABS1→partner) and Y-score (partner→CABS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PSKH2 →	+0.026	+5.472	<.001	<.001	3	2
LARGE_INTESTINE	TRIM49C →	+0.007	+3.345	<.001	.007	3	1
LUNG_NSCLC_LUAD	KRT28 →	+0.006	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	TEX33 →	+0.027	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	MBD3L4 →	+0.017	+5.266	<.001	.001	3	1
BREAST	ASB17 →	+0.032	+5.169	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

PSKH2 by CABS1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →