CA9

Across TCGA patient cohorts, CA9 protein abundance is significantly associated with the RNA expression of many other genes, with 9,372 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CA9-associated genes across cancer lineages are PFKFB4, MIR210HG, and PDK1. Each is linked with CA9 in more than 7 cancer types. Because this analysis shows association rather than direction, both CA9-to-partner and partner-to-CA9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA9 versus PFKFB4 in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA9→partner) and Y-score (partner→CA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PFKFB4 →	+1.043	+0.669	.001	.005	2	8
LSCC	MIR210HG →	+1.001	+1.095	<.001	<.001	3	7
GBM	PDK1 →	+0.894	+1.123	<.001	<.001	3	6
HNSC	PGK1 →	+1.073	+0.944	<.001	<.001	3	6
GBM	HILPDA →	+1.752	+1.576	<.001	<.001	3	6
HNSC	P4HA1 →	+0.782	+0.768	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,372 associations by consensus.

CA9 vs PFKFB4 — OV

Explore this scatter interactively →