CA9

Across TCGA patient cohorts, CA9 mutation is significantly associated with the RNA expression of many other genes, with 4,511 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CA9-associated genes across cancer lineages are RNU6-1297P, LINC01955, and RARRES2P10. Each is linked with CA9 in more than 3 cancer types. Because this analysis shows association rather than direction, both CA9-to-partner and partner-to-CA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1297P grouped by CA9-low versus CA9-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA9→partner) and Y-score (partner→CA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1297P →	+0.780	+3.793	<.001	.005	3	4
LIHC	LINC01955 →	+0.113	+4.567	<.001	.004	3	2
LIHC	RARRES2P10 →	+0.582	+4.174	.003	.009	3	2
UCEC	HSPE1-MOB4 →	+0.144	+2.214	.001	<.001	3	2
UCEC	ZNHIT3 →	+0.433	+2.269	.001	.001	3	2
UCEC	HNRNPCL3 →	+0.039	+2.001	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,511 associations by consensus.

RNU6-1297P by CA9 expression — LUAD

Explore this box plot interactively →