C9orf85

Across TCGA patient cohorts, C9orf85 protein abundance is significantly associated with the RNA expression of many other genes, with 2,923 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C9orf85-associated genes across cancer lineages are SPR, GRHL1, and ALG3. Each is linked with C9orf85 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf85-to-partner and partner-to-C9orf85 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf85 versus SPR in LSCC, with a Pearson correlation of 0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf85→partner) and Y-score (partner→C9orf85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPR →	+0.565	+0.305	.005	.008	3	2
LSCC	GRHL1 →	+0.789	+0.342	<.001	<.001	3	2
LSCC	ALG3 →	+0.716	+0.296	<.001	<.001	3	2
LSCC	CHCHD2P5 →	+0.439	+0.314	.003	.002	3	2
LSCC	C5orf34-AS1 →	+0.781	+0.307	.001	<.001	3	2
LSCC	KDM7A-DT →	+0.687	+0.388	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,923 associations by consensus.

C9orf85 vs SPR — LSCC

Explore this scatter interactively →