C9orf16

Across TCGA patient cohorts, C9orf16 protein abundance is significantly associated with the RNA expression of many other genes, with 7,983 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C9orf16-associated genes across cancer lineages are RANP6, TOX3, and TRIM32. Each is linked with C9orf16 in more than 2 cancer types. Because this analysis shows association rather than direction, both C9orf16-to-partner and partner-to-C9orf16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf16 versus RANP6 in BRCA, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf16→partner) and Y-score (partner→C9orf16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RANP6 →	-1.364	-0.454	<.001	<.001	3	3
BRCA	TOX3 →	+0.963	+0.375	<.001	<.001	3	3
UCEC	TRIM32 →	+0.462	+0.341	<.001	.001	3	3
BRCA	MOAP1 →	+0.558	+0.402	<.001	<.001	3	3
OV	SARAF →	+1.236	+1.087	<.001	.006	3	3
GBM	TMEM255A →	+0.837	+0.303	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,983 associations by consensus.

C9orf16 vs RANP6 — BRCA

Explore this scatter interactively →