Q-omics provides the consensus-scored RANP6 profile across patient tissues and cancer cell-line models. RANP6 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, RANP6 is differentially expressed in 8, with the highest sampling consensus in HNSC. Additionally, RANP6 RNA expression shows 11,225 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and HNSC as cancer lineages where RANP6 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RANP6 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RANP6 survival associations across molecular data types. RANP6 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RANP6 RNA expression–survival associations across cancer types. High RANP6 expression shows unfavorable associations in ACC, LIHC, LUAD and KIRC, but favorable associations in UCEC and THCA. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for RANP6 RNA expression.
This table summarizes RANP6 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for RANP6. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RANP6 shows higher tumor expression in HNSC, COAD, LUAD, BRCA, LUSC and READ. The HNSC box plot shows higher RANP6 RNA expression in tumor versus normal tissue (log2 FC = +0.287, t-test p < 0.001).
This table shows molecular features associated with RANP6 in patient tissues and cancer cell lines. In patient samples, RANP6 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
