C8orf87

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C8orf87 mutation is significantly associated with the RNA expression of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C8orf87-associated genes across cancer lineages are RN7SL134P, RN7SL25P, and EML2-AS1. Each is linked with C8orf87 in more than 1 cancer types. Because this analysis shows association rather than direction, both C8orf87-to-partner and partner-to-C8orf87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by C8orf87-low versus C8orf87-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf87→partner) and Y-score (partner→C8orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL134P →+0.326+3.599<.001.00731
UCECRN7SL25P →+0.515+3.899.001.00431
UCECEML2-AS1 →+0.141+3.914<.001.00431
UCECHMGB1P50 →+0.217+3.413.007.00631
UCECMIR7976 →+1.025+4.453<.001<.00131
UCECRPS29P32 →+0.778+3.599<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

RN7SL134P by C8orf87 expression — UCEC

Box plot of RN7SL134P in C8orf87-low vs C8orf87-high samples in UCEC.

Explore this box plot interactively →

Exploration