C8B

Across TCGA patient cohorts, C8B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,712 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C8B-associated proteins across cancer lineages are ISOC2, ZNF318_S2101, and OPLAH_T151. Each is linked with C8B in more than 3 cancer types. Because this analysis shows association rather than direction, both C8B-to-partner and partner-to-C8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C8B versus ISOC2 in OV, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C8B→partner) and Y-score (partner→C8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ISOC2 →	-0.429	-0.049	.006	.008	3	4
LSCC	ZNF318_S2101 →	-0.709	-0.590	<.001	<.001	3	3
OV	OPLAH_T151 →	-0.913	-0.053	<.001	.004	3	3
LSCC	CENPI_S284 →	-1.086	-0.550	<.001	<.001	3	3
COAD	CFI →	+0.598	+0.031	.003	.002	3	3
LSCC	AHCTF1_S1160 →	-0.698	-0.731	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,712 associations by consensus.

C8B vs ISOC2 — OV

Explore this scatter interactively →