C8B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C8B protein abundance is significantly associated with the RNA expression of many other genes, with 14,327 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C8B-associated genes across cancer lineages are MEIS3, SERPINE1, and FN1. Each is linked with C8B in more than 8 cancer types. Because this analysis shows association rather than direction, both C8B-to-partner and partner-to-C8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C8B versus MEIS3 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8B→partner) and Y-score (partner→C8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMEIS3 →+1.106+0.545<.001<.00139
OVSERPINE1 →+1.852+0.522<.001<.00139
COADFN1 →+2.456+0.730<.001<.00139
OVINHBA →+1.757+0.509<.001<.00139
OVCD93 →+0.920+0.622<.001<.00139
OVCOL5A1 →+2.160+0.716<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,327 associations by consensus.

C8B vs MEIS3 — OV

Per-sample scatter of C8B vs MEIS3 in OV (Pearson r = 0.42).

Explore this scatter interactively →

Exploration