C8B

Across TCGA cell cohorts, C8B RNA expression is significantly associated with the go_rna of many other GO terms, with 408 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible C8B-associated GO terms across cancer lineages are Glucuronate metabolic process, Positive regulation of natural killer cell differentiation, and Positive regulation of nitric oxide biosynthetic process. Each is linked with C8B in more than 2 cancer types. Because this analysis shows association rather than direction, both C8B-to-partner and partner-to-C8B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glucuronate metabolic process grouped by C8B-low versus C8B-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C8B→partner) and Y-score (partner→C8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Glucuronate metabolic process →	+0.140	+1.619	.002	.007	3	3
LIVER	Positive regulation of natural killer cell differentiation →	-1.077	-1.692	.001	.001	3	3
LIVER	Positive regulation of nitric oxide biosynthetic process →	+0.119	+1.145	<.001	.003	3	3
LIVER	Negative regulation of cell adhesion molecule production →	+1.222	+1.088	.001	.005	3	3
LIVER	Monocarboxylic acid catabolic process →	+0.061	+1.181	.003	.002	3	2
LIVER	Blood coagulation, common pathway →	+1.438	+1.093	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 408 associations by consensus.

Glucuronate metabolic process by C8B expression — LIVER

Explore this box plot interactively →