C7orf77

Across TCGA patient cohorts, C7orf77 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C7orf77-associated genes across cancer lineages are RNU6-271P, RNU6-1175P, and RNU6-43P. Each is linked with C7orf77 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf77-to-partner and partner-to-C7orf77 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-271P grouped by C7orf77-low versus C7orf77-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf77→partner) and Y-score (partner→C7orf77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-271P →	+0.685	+4.852	<.001	.006	3	1
UCEC	RNU6-1175P →	+0.536	+5.027	<.001	.004	3	1
UCEC	RNU6-43P →	+0.759	+4.349	.001	.007	3	1
UCEC	TRAJ11 →	+1.129	+4.398	<.001	.006	3	1
UCEC	NDUFA3P3 →	+0.496	+5.003	<.001	.002	3	1
UCEC	SFPQP1 →	+0.080	+4.326	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

RNU6-271P by C7orf77 expression — UCEC

Explore this box plot interactively →