Across TCGA patient cohorts, C7orf66 mutation is significantly associated with the RNA expression of many other genes, with 96 significant associations in total. COAD shows the largest number of these associations.

The most reproducible C7orf66-associated genes across cancer lineages are SEPTIN14P24, RNU7-80P, and JPT1P1. Each is linked with C7orf66 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf66-to-partner and partner-to-C7orf66 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf66→partner) and Y-score (partner→C7orf66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SEPTIN14P24 →	+0.397	+5.928	<.001	<.001	3	2
COAD	RNU7-80P →	+1.069	+4.308	<.001	.009	3	2
UCEC	JPT1P1 →	+0.290	+2.845	.002	.009	3	2
SKCM	LRRFIP2P1 →	+0.024	+5.643	<.001	<.001	3	1
SKCM	SNORD13P1 →	+0.655	+3.044	<.001	.005	3	1
SKCM	CALHM6-AS1 →	+0.155	+2.851	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

Exploration

C7orf66 survival (RNA) · tumor vs normal (RNA) · all C7orf66 data types