C7orf26

Across TCGA patient cohorts, C7orf26 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C7orf26-associated genes across cancer lineages are eEF2, ETS-1, and MEK1. Each is linked with C7orf26 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf26-to-partner and partner-to-C7orf26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by C7orf26-low versus C7orf26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf26→partner) and Y-score (partner→C7orf26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.447	+3.169	.022	.020	3	1
UCEC	ETS-1 →	+0.359	+3.000	.040	.036	3	1
UCEC	MEK1 →	+0.605	+3.169	.002	.019	3	1
UCEC	p62 Lck ligand →	+0.616	+3.179	<.001	.010	3	1
UCEC	PDCD4 →	-0.800	-2.999	.001	.035	3	1
UCEC	PEA-15_pS116 →	+0.436	+3.169	.023	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

eEF2 by C7orf26 expression — UCEC

Explore this box plot interactively →