C7orf26

Across TCGA pan-cancer cohorts, C7orf26 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated C7orf26 data layer compared with 1 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher C7orf26 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C7orf26 expression acts as an unfavorable survival marker, although some lineages such as PAAD and THYM show a favorable association.

KICH, PAAD, and HNSC are the cancer types where C7orf26 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Median	III,IV	0.468	1.000	.001	85	view →
PAAD	DFS	Median	All	0.465	0.201	<.001	64	view →
HNSC	OS	Median	All	0.707	0.792	.003	46	view →
ACC	DFS	Median	All	0.278	0.636	<.001	45	view →
LIHC	DFS	Median	All	0.360	0.507	<.001	43	view →
LGG	DFS	Median	All	0.650	0.804	.001	31	view →
THYM	OS	Median	All	0.966	0.765	.002	29	view →
MESO	DFS	Median	II,III,IV	0.309	0.591	.020	22	view →
KIRC	DFS	Tertile	All	0.736	0.524	.012	18	view →
CHOL	DFS	Quartile	All	0.797	0.082	.006	18	view →
PRAD	DFS	Median	All	0.846	0.924	.005	18	view →
SCLC	OS	Median	II,III,IV	1.000	0.462	.005	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

C7orf26–KICH (OS)

Open the KICH breakdown →