C7orf26

Across TCGA pan-cancer cohorts, C7orf26 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of C7orf26’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where C7orf26 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C7orf26 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, LIHC, and COAD are the cancer types where C7orf26 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C7orf26 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.434	<.001	11	view →
LIHC	Female	II,III,IV	+0.974	<.001	9	view →
COAD	Female	All	+0.669	<.001	9	view →
THCA	Female	All	−0.270	<.001	9	view →
HNSC	Male	All	+0.621	<.001	8	view →
STAD	Male	II,III,IV	+1.072	<.001	6	view →
CHOL	All	All	+1.825	<.001	5	view →
READ	All	All	+0.456	.002	5	view →
ESCA	All	All	+0.621	.002	2	view →
LUSC	Male	All	+0.200	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

C7orf26–KIRC

Open the KIRC breakdown →