C7orf26

Across TCGA cell cohorts, C7orf26 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C7orf26-associated genes across cancer lineages are PFN3, C11orf97, and PF4V1. Each is linked with C7orf26 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf26-to-partner and partner-to-C7orf26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PFN3 grouped by C7orf26-low versus C7orf26-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf26→partner) and Y-score (partner→C7orf26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PFN3 →	+0.057	+4.450	<.001	.004	3	2
BLOOD_Lymphoma	C11orf97 →	+2.118	+5.209	<.001	.005	3	2
LARGE_INTESTINE	PF4V1 →	+0.297	+3.793	<.001	.007	3	1
LARGE_INTESTINE	MYOD1 →	+0.012	+3.684	.001	.006	3	1
LARGE_INTESTINE	SSMEM1 →	+0.023	+3.707	.008	.009	3	1
LARGE_INTESTINE	CPLX4 →	+0.024	+4.392	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

PFN3 by C7orf26 expression — OVARY

Explore this box plot interactively →