C7orf25

Across TCGA patient cohorts, C7orf25 mutation is significantly associated with the RNA expression of many other genes, with 4,240 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C7orf25-associated genes across cancer lineages are RNU1-48P, VN1R91P, and RNU6-1101P. Each is linked with C7orf25 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf25-to-partner and partner-to-C7orf25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-48P grouped by C7orf25-low versus C7orf25-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf25→partner) and Y-score (partner→C7orf25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU1-48P →	+0.199	+7.930	<.001	.008	3	2
UCEC	VN1R91P →	+0.121	+2.188	<.001	.005	3	2
LUSC	RNU6-1101P →	+0.651	+6.906	<.001	<.001	3	2
SKCM	MIR668 →	+0.373	+7.816	<.001	.008	3	1
SKCM	OR8B4 →	+0.039	+7.816	<.001	.008	3	1
HNSC	LONRF2P2 →	+0.094	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,240 associations by consensus.

RNU1-48P by C7orf25 expression — LUAD

Explore this box plot interactively →