C7orf25

Across TCGA cell cohorts, C7orf25 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C7orf25-associated genes across cancer lineages are SH3GL2, PHF12, and MAGEB4. Each is linked with C7orf25 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf25-to-partner and partner-to-C7orf25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SH3GL2 grouped by C7orf25-low versus C7orf25-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf25→partner) and Y-score (partner→C7orf25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SH3GL2 →	+1.496	+3.667	<.001	<.001	3	1
LARGE_INTESTINE	PHF12 →	+0.668	+3.137	.006	.007	3	1
LARGE_INTESTINE	MAGEB4 →	+0.011	+3.415	<.001	.001	3	1
LARGE_INTESTINE	SAXO1 →	+0.038	+2.819	.002	.006	3	1
LARGE_INTESTINE	FAM153B →	+0.448	+2.841	<.001	.004	3	1
LARGE_INTESTINE	MINAR2 →	+0.024	+2.560	.006	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

SH3GL2 by C7orf25 expression — LARGE_INTESTINE

Explore this box plot interactively →