Across TCGA patient cohorts, C6orf58 protein abundance is significantly associated with the RNA expression of many other genes, with 699 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible C6orf58-associated genes across cancer lineages are C22orf31, CHORDC1, and ODF1. Each is linked with C6orf58 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf58-to-partner and partner-to-C6orf58 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf58→partner) and Y-score (partner→C6orf58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	C22orf31 →	+0.219	+1.249	.002	.005	3	1
PDAC	CHORDC1 →	+0.577	+0.896	.001	.003	3	1
PDAC	ODF1 →	+0.075	+1.991	.005	<.001	3	1
PDAC	TP53TG3D →	+0.091	+0.908	<.001	.007	3	1
PDAC	LEMD1-AS1 →	-0.772	-0.836	.003	.003	3	1
PDAC	RPSAP60 →	-0.478	-1.112	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 699 associations by consensus.

Exploration

C6orf58 survival (RNA) · tumor vs normal (RNA) · all C6orf58 data types