C6orf52

Across TCGA patient cohorts, C6orf52 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C6orf52-associated genes across cancer lineages are AKR1B10P2, MIR4662B, and MIR5695. Each is linked with C6orf52 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf52-to-partner and partner-to-C6orf52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AKR1B10P2 grouped by C6orf52-low versus C6orf52-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf52→partner) and Y-score (partner→C6orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AKR1B10P2 →	+0.074	+3.358	<.001	.006	3	1
UCEC	MIR4662B →	+0.272	+4.069	<.001	.008	3	1
UCEC	MIR5695 →	+0.771	+3.315	<.001	.001	3	1
UCEC	RNY3P11 →	+0.303	+3.484	.001	.004	3	1
UCEC	RNA5SP245 →	+0.807	+2.861	<.001	.009	3	1
UCEC	RNU1-84P →	+0.279	+3.242	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

AKR1B10P2 by C6orf52 expression — UCEC

Explore this box plot interactively →