Across TCGA patient cohorts, C6orf141 protein abundance is significantly associated with the RNA expression of many other genes, with 816 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible C6orf141-associated genes across cancer lineages are POLR3GL, CCL24, and RPA3. Each is linked with C6orf141 in more than 1 cancer types. Because this analysis shows association rather than direction, both C6orf141-to-partner and partner-to-C6orf141 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C6orf141→partner) and Y-score (partner→C6orf141) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	POLR3GL →	-0.998	-1.466	.007	.004	3	2
LSCC	CCL24 →	+1.193	+0.926	<.001	.004	3	1
LSCC	RPA3 →	+0.767	+1.211	.004	.001	3	1
LSCC	HSPE1 →	+0.916	+1.003	.003	.006	3	1
LSCC	TMEM255A →	-1.124	-1.027	.005	<.001	3	1
LSCC	VPREB3 →	-1.073	-0.917	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 816 associations by consensus.

Exploration

C6orf141 survival (RNA) · tumor vs normal (RNA) · all C6orf141 data types