C6

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C6 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,762 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C6-associated proteins across cancer lineages are TNS2, PGM5, and TNS2_S120. Each is linked with C6 in more than 7 cancer types. Because this analysis shows association rather than direction, both C6-to-partner and partner-to-C6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C6 versus TNS2 in OV, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C6→partner) and Y-score (partner→C6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVTNS2 →+0.368+0.798<.001<.00138
HNSCPGM5 →+0.984+0.530<.001<.00138
COADTNS2_S120 →+0.493+0.565<.001<.00137
OVATAD2_S342 →-1.427-0.803<.001.00237
OVSERPINA5 →+0.836+0.790.003.00237
LSCCUTP4 →-0.271-0.589<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,762 associations by consensus.

C6 vs TNS2 — OV

Per-sample scatter of C6 vs TNS2 in OV (Pearson r = 0.48).

Explore this scatter interactively →

Exploration