C5orf64

Across TCGA cell cohorts, C5orf64 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C5orf64-associated genes across cancer lineages are CYP2A13, C1QC, and BPIFA1. Each is linked with C5orf64 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf64-to-partner and partner-to-C5orf64 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYP2A13 grouped by C5orf64-low versus C5orf64-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf64→partner) and Y-score (partner→C5orf64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CYP2A13 →	+0.021	+4.415	<.001	.007	3	2
LARGE_INTESTINE	C1QC →	+0.066	+4.273	<.001	.006	3	1
LARGE_INTESTINE	BPIFA1 →	+0.178	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CYP2A13 by C5orf64 expression — LARGE_INTESTINE

Explore this box plot interactively →