C5orf63

Across TCGA patient cohorts, C5orf63 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,741 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible C5orf63-associated proteins across cancer lineages are PYGL, TERF2, and MSH3. Each is linked with C5orf63 in more than 4 cancer types. Because this analysis shows association rather than direction, both C5orf63-to-partner and partner-to-C5orf63 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C5orf63 versus PYGL in UCEC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf63→partner) and Y-score (partner→C5orf63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PYGL →	-0.471	-0.610	<.001	<.001	3	5
GBM	TERF2 →	+0.454	+0.844	<.001	<.001	3	5
BRCA	MSH3 →	+0.287	+0.952	<.001	<.001	3	5
LSCC	CKAP4_S26 →	-0.614	-0.495	<.001	<.001	3	5
HNSC	TAF7 →	+0.252	+0.465	<.001	.004	3	5
PDAC	PPP1R18_S368 →	-0.564	-0.426	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,741 associations by consensus.

C5orf63 vs PYGL — UCEC

Explore this scatter interactively →