C5orf63

Across TCGA patient cohorts, C5orf63 protein abundance is significantly associated with the RNA expression of many other genes, with 182 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible C5orf63-associated genes across cancer lineages are BCL2L2, DUSP5, and DHRS1. Each is linked with C5orf63 in more than 1 cancer types. Because this analysis shows association rather than direction, both C5orf63-to-partner and partner-to-C5orf63 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C5orf63 versus BCL2L2 in LUAD, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf63→partner) and Y-score (partner→C5orf63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BCL2L2 →	+0.569	+0.608	.009	.008	3	1
LUAD	DUSP5 →	-1.042	-0.809	.009	.004	3	1
LUAD	DHRS1 →	+0.755	+0.839	<.001	.007	3	1
LUAD	SHROOM1 →	+1.230	+0.677	.007	.005	3	1
LUAD	FAAH2 →	+0.710	+0.611	.004	.008	3	1
LUAD	TC2N →	+1.594	+0.712	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 182 associations by consensus.

C5orf63 vs BCL2L2 — LUAD

Explore this scatter interactively →