C5orf63

Across TCGA cell cohorts, C5orf63 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,394 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C5orf63-associated GO terms across cancer lineages are Regulation of transcription elongation by RNA polymerase II, Establishment of protein localization to membrane, and Translational initiation. Each is linked with C5orf63 in more than 7 cancer types. Because this analysis shows association rather than direction, both C5orf63-to-partner and partner-to-C5orf63 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription elongation by RNA polymerase II grouped by C5orf63-low versus C5orf63-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C5orf63→partner) and Y-score (partner→C5orf63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of transcription elongation by RNA polymerase II →	+0.058	+1.516	.002	<.001	3	8
OVARY	Establishment of protein localization to membrane →	+0.051	+1.333	.001	.001	3	7
OVARY	Translational initiation →	+0.066	+1.042	<.001	.003	3	7
SKIN	Regulation of protein localization to Cajal body →	+0.050	+0.993	.002	<.001	3	7
SKIN	Positive regulation of protein localization to Cajal body →	+0.050	+0.993	.002	<.001	3	7
BREAST	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.066	+0.943	.005	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,394 associations by consensus.

Regulation of transcription elongation by RNA polymerase II by C5orf63 expression — OVARY

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