C4orf51

Across TCGA patient cohorts, C4orf51 mutation is significantly associated with the RNA expression of many other genes, with 410 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4orf51-associated genes across cancer lineages are MIR1267, SNORD116-12, and MIR615. Each is linked with C4orf51 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf51-to-partner and partner-to-C4orf51 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1267 grouped by C4orf51-low versus C4orf51-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf51→partner) and Y-score (partner→C4orf51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR1267 →	+0.561	+7.040	<.001	<.001	3	2
BLCA	SNORD116-12 →	+0.408	+5.497	<.001	.004	3	2
UCEC	MIR615 →	+0.313	+2.910	<.001	.004	3	2
UCEC	MLLT10P2 →	+0.313	+3.434	<.001	.001	3	2
BLCA	RNU6-1086P →	+0.436	+5.251	<.001	.006	3	1
BLCA	LRRC2P1 →	+0.045	+6.814	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 410 associations by consensus.

MIR1267 by C4orf51 expression — BLCA

Explore this box plot interactively →