C4orf50

Across TCGA cell cohorts, C4orf50 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,268 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C4orf50-associated GO terms across cancer lineages are Primary alcohol biosynthetic process, CDP-choline pathway, and Regulation of cytoplasmic mRNA processing body assembly. Each is linked with C4orf50 in more than 5 cancer types. Because this analysis shows association rather than direction, both C4orf50-to-partner and partner-to-C4orf50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Primary alcohol biosynthetic process grouped by C4orf50-low versus C4orf50-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf50→partner) and Y-score (partner→C4orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Primary alcohol biosynthetic process →	-0.189	-0.053	.003	.009	2	6
BONE	CDP-choline pathway →	-0.187	-0.042	<.001	.006	3	4
CNS	Regulation of cytoplasmic mRNA processing body assembly →	+0.087	+0.011	<.001	.006	3	4
LUNG_SCLC	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.092	+0.553	.001	.001	3	4
CNS	Optic nerve development →	-0.269	-0.015	<.001	<.001	3	4
CNS	Spliceosomal complex assembly →	+0.054	+0.010	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,268 associations by consensus.

Primary alcohol biosynthetic process by C4orf50 expression — SOFT_TISSUE

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