C4orf45

Across TCGA patient cohorts, C4orf45 mutation is significantly associated with the RNA expression of many other genes, with 1,064 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4orf45-associated genes across cancer lineages are RN7SKP77, RNU6-1169P, and MIR629. Each is linked with C4orf45 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf45-to-partner and partner-to-C4orf45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP77 grouped by C4orf45-low versus C4orf45-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf45→partner) and Y-score (partner→C4orf45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SKP77 →	+0.167	+7.357	<.001	<.001	3	2
SKCM	RNU6-1169P →	+0.365	+5.362	<.001	.005	3	2
LIHC	MIR629 →	+0.573	+6.676	<.001	<.001	3	2
SKCM	NDUFA4P2 →	+0.177	+5.037	<.001	.009	3	2
LIHC	RN7SKP219 →	+0.156	+5.033	<.001	.009	3	1
LIHC	IGHVIV-44-1 →	+0.134	+5.108	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,064 associations by consensus.

RN7SKP77 by C4orf45 expression — HNSC

Explore this box plot interactively →