C4orf19

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C4orf19 mutation is significantly associated with the RNA expression of many other genes, with 121 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C4orf19-associated genes across cancer lineages are RNU6-1215P, RNA5SP519, and MIR520A. Each is linked with C4orf19 in more than 1 cancer types. Because this analysis shows association rather than direction, both C4orf19-to-partner and partner-to-C4orf19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1215P grouped by C4orf19-low versus C4orf19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C4orf19→partner) and Y-score (partner→C4orf19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-1215P →+0.500+2.611.003.00532
UCECRNA5SP519 →+0.537+3.398<.001.00132
LGGMIR520A →+0.393+7.977<.001.00731
LGGMIR548I3 →+0.248+7.977<.001.00731
LGGOFD1P13Y →+0.034+7.977<.001.00731
LGGUSP9YP10 →+0.049+7.977<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 121 associations by consensus.

RNU6-1215P by C4orf19 expression — UCEC

Box plot of RNU6-1215P in C4orf19-low vs C4orf19-high samples in UCEC.

Explore this box plot interactively →

Exploration