C4A-AS1

Across TCGA patient cohorts, C4A-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,105 significant associations in total. LGG shows the largest number of these associations.

The most reproducible C4A-AS1-associated GO terms across cancer lineages are Regulation of apoptotic cell clearance, Positive regulation of apoptotic cell clearance, and Detection of external biotic stimulus. Each is linked with C4A-AS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both C4A-AS1-to-partner and partner-to-C4A-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of apoptotic cell clearance grouped by C4A-AS1-low versus C4A-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C4A-AS1→partner) and Y-score (partner→C4A-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of apoptotic cell clearance →	+0.133	+0.003	<.001	.005	2	6
ESCA	Positive regulation of apoptotic cell clearance →	+0.145	+0.005	<.001	.009	1	6
LGG	Detection of external biotic stimulus →	+0.032	+0.002	.004	.002	2	4
MESO	Protein K29-linked deubiquitination →	-0.051	-0.028	<.001	<.001	3	2
LGG	Regulation of myoblast fusion →	+0.032	+0.003	.002	.002	3	2
MESO	Retinol metabolic process →	+0.052	+0.024	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,105 associations by consensus.

Regulation of apoptotic cell clearance by C4A-AS1 expression — ESCA

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