C4A-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, C4A-AS1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of C4A-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where C4A-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C4A-AS1 is over-expressed in tumor.

LIHC are the cancer types where C4A-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C4A-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LIHCAllAll+0.012.0331view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

C4A-AS1–LIHC

Tumor-vs-normal expression box plot for C4A-AS1 RNA in LIHC.

Open the LIHC breakdown →

Exploration