C3orf85

Across TCGA cell cohorts, C3orf85 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,460 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C3orf85-associated GO terms across cancer lineages are Renal D-glucose absorption, Negative regulation of macrophage cytokine production, and Organic acid catabolic process. Each is linked with C3orf85 in more than 3 cancer types. Because this analysis shows association rather than direction, both C3orf85-to-partner and partner-to-C3orf85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal D-glucose absorption grouped by C3orf85-low versus C3orf85-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C3orf85→partner) and Y-score (partner→C3orf85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Renal D-glucose absorption →	+1.034	+1.305	<.001	<.001	3	4
SKIN	Negative regulation of macrophage cytokine production →	-0.183	-0.259	<.001	.001	3	3
LARGE_INTESTINE	Organic acid catabolic process →	+0.049	+1.245	<.001	<.001	3	3
SKIN	Regulation of receptor binding →	-0.436	-0.229	.001	.006	3	3
SKIN	Positive regulation of extracellular matrix assembly →	-0.107	-0.242	.007	.003	3	3
LARGE_INTESTINE	Carboxylic acid catabolic process →	+0.049	+1.245	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,460 associations by consensus.

Renal D-glucose absorption by C3orf85 expression — LARGE_INTESTINE

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