C3P1

Across TCGA patient cohorts, C3P1 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C3P1-associated genes across cancer lineages are eEF2, Gab2, and GATA6. Each is linked with C3P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both C3P1-to-partner and partner-to-C3P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by C3P1-low versus C3P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C3P1→partner) and Y-score (partner→C3P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.362	+3.169	.014	.018	3	1
UCEC	Gab2 →	+0.376	+1.807	.010	.027	3	1
UCEC	GATA6 →	-0.192	-2.215	.003	.010	3	1
UCEC	ACC1 →	+0.310	+1.807	.039	.027	3	1
UCEC	ACVRL1 →	-0.115	-2.439	.040	.019	3	1
UCEC	JNK_pT183_Y185 →	-0.223	-2.308	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

eEF2 by C3P1 expression — UCEC

Explore this box plot interactively →